Well characterized and relevant animal models of disease are critical for successful development of antimicrobial drugs and vaccines. IBT Bioservices has established 15+ highly relevant mouse models of infection up to BSL-2 containment level in-house, and provides BSL-3 and BSL-4 models through partners. IBT staff have decades of combined experience with animal models of viral and bacterial infections in BSL-2, BSL-3, and BSL-4 settings.
Immunogenicity, pharmacokinetics and toxicity testing are also key studies for drug and vaccine development. IBT Bioservices can collect samples and perform a wide range of tests such as induction of cytokines/biomarkers, immune responses, drug bioavailability and half-life, gross toxicity, etc.
We regularly develop new animal models, assays and readouts, often per client request. If you don't see what you need, or have any other questions, please contact us.
Virus Infection Models
Bacterial Infection Models
Animal Species and Readouts
|Animal Species||Mouse strains: AG129, BALB/c, C57BL/6, ICR, others
Cotton rat: S. hispidus
|Readouts||Temperature monitoring via microchip; Microbial burden in blood and organs; Cytokines; Biomarkers|