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In Vitro Antiviral Testing

Well-characterized assays for a growing selection of viruses   Now Available! VSV-SARS-CoV2 Neutralization Assay

In Vitro Antiviral Testing

Assays for a wide selection of gram-positive and gram-negative bacteria

Reagents

Now Available!  New Reagents for Coronavirus research    Full-Length Spike Protein, Soluble Receptor Binding Domain, Nucleocapsid Protein, and Polyclonal Antibodies.

Animal Models

Antiviral & antibacterial disease models – Immunogenicity testing, Pharmacokinetics & toxicity

Assay & Protein Services

Custom development, analysis and expression services

About IBT

The IBT Bioservices mission is to provide top client value by applying our infectious disease expertise, collaborative scientific interaction, and a flexible, cost-effective business model. The result is timely and relevant data for our clients’ needs.

Our scientists are leaders in their areas and can provide the highest level of expertise for your R&D programs. Read more about IBT.

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Fig. 1 Survival after challenge with INFV H1N1 A/Pert/261/2009 (Tamiflu-resistant strain). Inoculum 1xLD90=1.0E+05 PFU/mouse
Survival after challenge with INFV H1N1 A/Pert/261/2009 (Tamiflu-resistant strain) 1.0E+05 PFU/mouse
Survival and weight change in BALB/c mice challenged with INFV A/ Texas/36/91 (H1N1) and treated with antiviral Osletamivir Phosphate (Tamiflu)
Lung viral load and Survival (30 % weight loss cut-off) in BALB/c mice challenged with INFV H3N2 A/HK/1/68.

Alpha (UK) – B. 1.1.7 / 501Y.V1

amino acid mutations: del69–70 HV, del144 Y, N501Y, A570D, D614G, P681H, T761I, S982A, D1118H

Beta (South Africa) – B.1.351

amino acid mutations: K417N, E484K, N501Y, D614G, A701V

Gamma (Brazil) – P.1

amino acid mutations: L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I

Epsilon (Ca, USA) B.1.427

amino acid mutations: L452R, D614G

SARS-CoV-2 Parental Strain Wild Type (Wuhan)
SARS-CoV-2 D614G Variant

amino acid mutations: D614G

Epsilon (Ca, USA) B.1.429

amino acid mutations: S13I, W152C, L452R, D614G

SARS-CoV-2 Delta Variant

amino acid mutations: L452R, E484Q