Enterotoxigenic E. Coli Model

For the ETEC Intestinal colonization model, normal flora is eliminated with streptomy- cin and cimetidine is used for stomach deacidification. Mice are then inoculated with ETEC H10407 by gastric gavage and colonization is examined at different time points post chal- lenge by measurement of CFUs in the intestine. Bacterial shedding as well as antibody re- sponse can be measured in stool samples. Lethality endpoint can be determined using high dose challenge.

IBT Bioservices continues to conduct critical work as an essential business under the State of Maryland’s COVID-19 response directive. We have implemented a risk management plan and are continually monitoring the situation to ensure continuation of research according to public health services recommended best-practices for keeping our employees and the community safe. 

The IBT Bioservices team will continue to deliver high quality products and services for every project. If you have any questions contact us at Services@IBTBioservices.com