Assay Details

S. aureus secretes a number of virulence factors, among the most prominent of which is the small β-barrel pore-forming toxin α-hemolysin (also known as alpha-toxin).

A rabbit red blood cell lysis assay has been developed to assess the neutralizing ability of antibodies in samples against alpha-toxin. Percentage lysis, percentage neutralization and the NT50 values for the samples (the dilution or concentration of the sample that gives 50% neutralization) can be calculated.

IBT Bioservices continues to conduct critical work as an essential business under the State of Maryland’s COVID-19 response directive. We have implemented a risk management plan and are continually monitoring the situation to ensure continuation of research according to public health services recommended best-practices for keeping our employees and the community safe. 

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