Assay Details

This assay tests the neutralization capacity of samples against S. aureus bi-component toxins (leukocidins and gamma-hemolysins) in a neutrophil-like induced HL-60 cell line. Leukocidins act synergistically in pairs to induce damage of monocytes, macrophages and neutrophils. Gamma-lysins also act synergistically but affect leukocytes as well as red blood cells.

We can test the neutralization ability of serum samples against the different toxin pairs Panton-Valentine leukocidin (PVL or LukSF), leukocidin ED (LukED), gamma-hemolysin HlgCB and gamma-hemolysin AB (HlgAB).

IBT Bioservices continues to conduct critical work as an essential business under the State of Maryland’s COVID-19 response directive. We have implemented a risk management plan and are continually monitoring the situation to ensure continuation of research according to public health services recommended best-practices for keeping our employees and the community safe. 

The IBT Bioservices team will continue to deliver high quality products and services for every project. If you have any questions contact us at Services@IBTBioservices.com