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Alphaviruses are arthropod-borne viruses that cause disease in humans and a wide range of domestic and agricultural animals. Interest in development of alphavirus therapeutics and vaccines has risen in recent years due to epidemics of Chikungunya virus (CHIKV) causing severe illness in Africa and Asia and concerns about possible use of Venezuelan equine encephalitis virus (VEE) as an agent of bioterrorism.  IBT’s alphavirus reagent line covers Chikungunya and Venezuelan Equine Encephalitis Virus.  Reagents include antisera and purified polyclonal antibodies. Specific targets include CHIKV, CHIKV E2 protein, and VEE.

If you have any questions or would like to inquire about discounts for bulk purchases, please contact us.

NotesProduct NameTargetCat #SizeDatasheetPriceBuy
Rabbit anti-Chikungunya (CHIKV) antiserumChikungunya Virus01-0008250 uL$420.00
Rabbit anti-Chikungunya (CHIKV) pAbChikungunya Virus04-0008500 ug$240.00
Rabbit anti-CHIKV E2 pAbChikungunya Virus0306-001100 ug$450.00
Rabbit anti-EEEV E2 GP pAbEastern Equine Encephalitis Virus0318-001100 ug$425.00
Rabbit anti-Venezuelan Equine Encephalitis (VEE) antiserumVenezuelan Equine Encephalitis Virus01-0002250 uL$396.00
Rabbit anti-Venezuelan Equine Encephalitis (VEE) pAbVenezuelan Equine Encephalitis Virus04-0002500 ug$240.00
Rabbit anti-WEEV E2 GP pAbWestern Equine Encephalitis Virus0319-001100 ug$425.00
Recombinant EEEV E2 GP (E3E2)Eastern Equine Encephalitis Virus0560-001100 ug$425.00
Recombinant WEEV E2 GP (E3E2)Western Equine Encephalitis Virus0561-001100 ug$425.00
Recombinant WEEV E2 GP (E3E2) - (mammalian)Western Equine Encephalitis Virus0562-001100 ug$425.00
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Fig. 1 Survival after challenge with INFV H1N1 A/Pert/261/2009 (Tamiflu-resistant strain). Inoculum 1xLD90=1.0E+05 PFU/mouse
Survival after challenge with INFV H1N1 A/Pert/261/2009 (Tamiflu-resistant strain) 1.0E+05 PFU/mouse
Survival and weight change in BALB/c mice challenged with INFV A/ Texas/36/91 (H1N1) and treated with antiviral Osletamivir Phosphate (Tamiflu)
Lung viral load and Survival (30 % weight loss cut-off) in BALB/c mice challenged with INFV H3N2 A/HK/1/68.

Alpha (UK) – B. 1.1.7 / 501Y.V1

amino acid mutations: del69–70 HV, del144 Y, N501Y, A570D, D614G, P681H, T761I, S982A, D1118H

Beta (South Africa) – B.1.351

amino acid mutations: K417N, E484K, N501Y, D614G, A701V

Gamma (Brazil) – P.1

amino acid mutations: L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I

Epsilon (Ca, USA) B.1.427

amino acid mutations: L452R, D614G

SARS-CoV-2 Parental Strain Wild Type (Wuhan)
SARS-CoV-2 D614G Variant

amino acid mutations: D614G

Epsilon (Ca, USA) B.1.429

amino acid mutations: S13I, W152C, L452R, D614G

SARS-CoV-2 Delta Variant

amino acid mutations: L452R, E484Q

Wishing You a Happy Thanskgiving!

In observance of Thanksgiving our offices will be closed Thursday November 24th through Sunday November 27th. We will resume normal business hours Monday November 28th. Please excuse any delayed responses during this period.

We look forward to assisting you with all your preclinical product and testing needs after the holiday. Happy Thanksgiving!

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